(P) Patient, Population, or Problem - How would you describe a group of patients similar to yours? Consider diagnosis, age, sex & demographics. What are the most important characteristics?
( I ) Intervention - What treatment or exposure are you considering?
(C) Comparison - This could be a different intervention, such as usual care, or placebo, a different medication, or even no intervention.
(O) Outcome - What are you planning to accomplish, measure, improve, or affect?
(T) Time - duration of the study
By CFCF (Own work) [CC BY-SA 4.0 (http://creativecommons.org/licenses/by-sa/4.0)], via Wikimedia Commons